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A STUDY ON THE INFLUENCE OF INFANT FORMULAS ON PLAQUE pH

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Abstract

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ÀúÀÚ´Â À¯¾Æ¿ë Á¶Á¦ºÐÀ¯¿Í ¿ìÀ¯º´ ¿ì½ÄÁõ°úÀÇ °ü·Ã¼º°ú ¿ìÀ¯ ´Ü¹éÁú°ú ´ç¿¡ ÀÇÇÑ À¯¾Æ¿ë
Á¶Á¦ºÐÀ¯ÀÇ ¿ì½Ä À¯¹ß ÀáÀ缺À» Æò°¡Çϱâ À§ÇØ ±¹³»¿¡¼­ ½ÃÆǵǴ 6°³ÀÇ ¼­·Î ´Ù¸¥ ±¹»ê À¯
¾Æ¿ë Á¶Á¦ºÐÀ¯(¿ìÀ¯ base À¯¾Æ¿ë Á¶Á¦ºÐÀ¯ 3Á¾, Äá base À¯¾Æ¿ë Á¶Á¦ºÐÀ¯ 1Á¾, ¿ìÀ¯ ´Ü¹éÁú
¿¡ ¾Ë·¹¸£±â°¡ Àְųª À¯´ç ºÒ³»Áõ(lactose intolerance)ÀÌ ÀÖ´Â À¯¾Æ¸¦ À§ÇÑ Æ¯¼ö À¯¾Æ¿ë Á¶
Á¦ºÐÀ¯ 2Á¾)¸¦ ´ë»óÀ¸·Î Invivo/In vitro combination techniqueÀ» ÀÌ¿ëÇÏ¿© °¢ À¯¾Æ¿ë Á¶Á¦
ºÐÀ¯·Î ±¸°­³» ¸°½º ÈÄ Ä¡Å pH º¯È­¿¡ ´ëÇÑ ¿µÇâÀ» ¿¬±¸ÇÏ¿© ´ÙÀ½°ú °°Àº °á·ÐÀ» ¾ò¾ú´Ù.
1. ½ÃÆǵǴ °¢±â ´Ù¸¥ ¹üÁÖ¿¡ ¼ÓÇÏ´Â 6°³ÀÇ À¯¾Æ¿ë Á¶Á¦ºÐÀ¯´Â ¸ðµÎ Ä¡ÅÂÀÇ pH¸¦ À¯ÀÇ
¼º ÀÖ°Ô ¶³¾î¶ß·ÈÀ¸¸ç(p<0.05) ¸°½º 1½Ã°£ ÈÄ¿¡µµ ´ëºÎºÐÀÇ ´ë»óÀÚ¿¡¼­ Ä¡Å pH´Â ȸº¹µÇ
Áö ¾Ê¾Ò´Ù.
2. Ä«¼¼ÀÎÀ» ÇÔÀ¯ÇÏÁö ¾ÊÀº Äá bag À¯¾Æ¿ë Á¶Á¦ºÐÀ¯¿Í Ä«¼¼ÀÎ °¡¼öºÐÇØ À¯¾Æ¿ë Á¶Á¦ºÐÀ¯
´Â Ä«¼¼ÀÎÀ» ÇÔÀ¯ÇÑ ¿ìÀ¯ base À¯¾Æ¿ë Á¶Á¦ºÐÀ¯º¸´Ù Ä¡ÅÂÀÇ pH¸¦ À¯ÀǼº ÀÖ°Ô ´õ ¸¹ÀÌ ¶³
¾î¶ß·È´Ù (p<0.05).
3. À¯¾Æ¿ë Á¶Á¦ºÐÀ¯ ³»ÀÇ ¿ìÀ¯ ´Ü¹éÁú Áß À¯Ã» ´Ü¹éÁúº¸´Ù´Â Ä«¼¼ÀÎÀÌ Ä¡Å pH º¯È­ÀÇ
¿ÏÈ­¿¡ ´õ ¿µÇâÀ» ¹ÌÄ¡´Â °ÍÀ¸·Î º¸À̸ç Ä«¼¼ÀÎÀ» °¡¼öºÐÇØÇÑ À¯¾Æ¿ë Á¶Á¦ºÐÀ¯¿¡¼­´Â ÀÌ·¯
ÇÑ Ä«¼¼ÀÎÀÇ ¿µÇâÀÌ ÁÙ¾îµé¾ú´Ù.
4. ´Ü¹éÁú Á¶¼ºÀÌ ºñ½ÁÇÑ »óÅ¿¡¼­ ÀÚ´ç(sucrose)À» Æ÷ÇÔÇÑ À¯¾Æ¿ë Á¶Á¦ºÐÀ¯´Â À¯´ç
(lactose)À» Æ÷ÇÔÇÑ À¯¾Æ¿ë Á¶Á¦ºÐÀ¯º¸´Ù Ä¡Å pH¸¦ ´õ ¶³¾î¶ß·ÈÀ¸³ª À¯ÀǼº ÀÖ´Â Â÷ÀÌ´Â
¾ø¾ú´Ù(p>0.05).
#ÃÊ·Ï#
Infant formula in nursing bottle, with inappropriate feeding habits, is major factor
associated with the development of nursing ca¥ãiris. Although each infant formula has
different carbohydrate and protein composition, studies comparing cariogenic potential of
many Korean-branded infant formulas are deficient. In addition, it is on the point of
belong difficult to evaluate the cariogenecity of milk due to development of many infant
formulas. In this study, to evaluate the cariogenic potential of many infant formulas,
after oral rinse with six Korean-branded infant formulas (three milk based formulas, one
soy based formula and two specific formulas for infants with allergy to milk protein and
with lactose intolerance) for ten adult volunteers (eight males and two females), plaque
pH change was measured with In vivo/in vitro combination technique and results were
as follows.
1. All six different kinds of Korean-branded commercial infant formulas dropped the
plaque pH significantly (p<0.05) and at an hour after rinse, plaque pH was not
recovered in most of subjects.
2. Soy based infant formula and casein-hydrolyzated infant formula containing no
casein dropped the plaque pH significantly more than milk based infant formula
containing casein (p<0.05).
3. In the milk protein of infant formulas, casein had more effect on buffering the pH
change of the infant formula than whey protein and casein-hydrolyzated infant formula
had a reduced effect of casein.
4. In infant formulas with similar protein composition, infant formula containing
sucrose dropped plaque pH more than infant formula containing lactose, but there was
no significant difference (p>0.05).

Å°¿öµå

infant formula; nursing caries; plaque pH; protein; carbohydrate;

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